Containers for Ophthalmic Preparations

  • Containers for Ophthalmic Preparations are specialized sterile containers designed to maintain product sterility, stability, and accurate dosing.
  • Containers for Ophthalmic Preparations must be non-reactive, tamper-evident, and suitable for single or multiple use.
  • Selecting appropriate containers is vital to ensure sterility, stability, and usability:

Containers for Ophthalmic Preparation:

Containers for Ophthalmic Preparations

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  1. Dropper Bottles (Low-Density Polyethylene – LDPE)

    • Commonly used for eye drops.
    • Designed to deliver controlled droplet size.
    • Must be compatible with the formulation (e.g., no leaching of plasticizers).
  2. Multidose vs. Single-Dose Containers

    • Multidose: Contain preservatives, used multiple times, have a built-in dropper tip.
    • Single-dose vials: Preservative-free, used once, typically come in plastic blow-fill-seal (BFS) packs.
  3. Collapsible Tubes (Aluminum or Plastic)

    • For eye ointments.
    • Must be sterile, often have a narrow nozzle to dispense small quantities.
  4. Large Plastic Bottles

    • For eye lotions/irrigations.
    • Must maintain sterility over the product shelf life (often single-use).

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