Cyclopentolate Hydrochloride

  • Cyclopentolate Hydrochloride is used in ophthalmology for pupil dilation and cycloplegia.
  • Cyclopentolate Hydrochloride is an anticholinergic blocking muscarinic receptors in the eye.

Chemical Formula:

  • C₁₇H₂₅NO₃·HCl

 Chemical Structure of Cyclopentolate Hydrochloride

Mechanism of Action of Cyclopentolate Hydrochloride:

  • Muscarinic receptor blocker (M3 predominant)
  • Shorter duration than atropine, longer than tropicamide

Therapeutic Uses of Cyclopentolate Hydrochloride:

  • Cycloplegic refraction in children
  • Mydriasis for diagnostic purposes
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Side Effects:

  • CNS stimulation (especially in children)
  • Tachycardia
  • Dry mouth
  • Photophobia

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