Diffusion Principles in Biological Systems
- S-3-PHYSICAL-PHARMACEUTICS
- Feb 28
- 1 min read
Buy Now the Hard Copy of notes for seamless and ad-free learning, Click Below!
Fick's Laws of Diffusion
A) First Law
States that the rate of diffusion is proportional to the concentration gradient.
Describes the flux of molecules:
J is the flux, D is the diffusion coefficient, is the concentration gradient.
B) Second Law
Explains that diffusion causes changes in concentration over time.
Permeability Coefficient (P)
Determines the rate at which a drug diffuses across a membrane.
Partition Coefficient (K)
Ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium.
Factors Affecting Diffusion Principles in Biological Systems
Molecular size, lipophilicity, ionization state, and membrane properties.
Buy Now the Hard Copy of notes for seamless and ad-free learning, Click Below!
Comentarios