Dimenhydrinate

Discover how Dimenhydrinate is used to prevent motion sickness and nausea, including its mechanism and therapeutic effects.

Structure of Dimenhydrinate

  • Dimenhydrinate is a combination of diphenhydramine and 8-chlorotheophylline.
  • It forms a hydrate salt, enhancing its pharmacokinetic properties.
  • Chemical Formula: C₁₉H₂₆ClN₃O·H₂O

Structure of Dimenhydrinate

Mode of Action

  • Acts primarily as an H₁-antagonist to reduce histamine-induced symptoms.
  • The theophylline component provides mild stimulant effects to counteract diphenhydramine-induced sedation, making it effective for motion sickness.
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Uses

  • Motion Sickness: Prevents and treats nausea, vomiting, and dizziness associated with travel.
  • Vertigo: Alleviates symptoms of vertigo and balance disorders.
  • Allergic Reactions: Provides relief from allergic symptoms with reduced sedation.

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