Discover how Dimenhydrinate is used to prevent motion sickness and nausea, including its mechanism and therapeutic effects.
Structure of Dimenhydrinate
- Dimenhydrinate is a combination of diphenhydramine and 8-chlorotheophylline.
- It forms a hydrate salt, enhancing its pharmacokinetic properties.
- Chemical Formula: C₁₉H₂₆ClN₃O·H₂O
Mode of Action
- Acts primarily as an H₁-antagonist to reduce histamine-induced symptoms.
- The theophylline component provides mild stimulant effects to counteract diphenhydramine-induced sedation, making it effective for motion sickness.
Uses
- Motion Sickness: Prevents and treats nausea, vomiting, and dizziness associated with travel.
- Vertigo: Alleviates symptoms of vertigo and balance disorders.
- Allergic Reactions: Provides relief from allergic symptoms with reduced sedation.
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