DNA (Deoxyribonucleic Acid): Structure & Functions

  • DNA, or Deoxyribonucleic Acid, is a long, double-stranded molecule that carries the genetic instructions used in the growth, development, functioning, and reproduction of all known living organisms and many viruses.
  • DNA (Deoxyribonucleic Acid) is composed of two strands forming a double helix, made up of repeating units called nucleotides.
  • Each nucleotide consists of a sugar (deoxyribose), a phosphate group, and one of four nitrogenous bases—adenine (A), thymine (T), cytosine (C), or guanine (G).

DNA (Deoxyribonucleic Acid) Structure

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Structure DNA (Deoxyribonucleic Acid):

  1. Double Helix:

    • DNA is composed of two long strands that form a double helix, which looks like a twisted ladder.
    • Backbone: Each strand consists of a sugar-phosphate backbone, with the sugar being deoxyribose.
    • Bases: Attached to each sugar is one of four nitrogenous bases: adenine (A), thymine (T), cytosine (C), and guanine (G).
    • Base Pairing: The strands are held together by hydrogen bonds between the bases, with A pairing with T and C pairing with G.
  2. Antiparallel Orientation:

    • The two strands run in opposite directions, one from 5′ to 3′ and the other from 3′ to 5′.
  3. Major and Minor Grooves:

    • The twisting of the helix creates grooves, which are the sites of protein binding for replication and transcription.
  4. Chromatin and Chromosomes:

Functions of DNA (Deoxyribonucleic Acid):

  1. Genetic Information Storage: DNA holds the genetic blueprint for the development, functioning, and reproduction of all living organisms and many viruses.
  2. Replication: DNA can replicate itself, ensuring that genetic information is passed from cell to cell and from generation to generation.
  3. Gene Expression: DNA sequences (genes) are transcribed into RNA, which then directs the synthesis of proteins.
  4. Regulation: DNA contains regulatory sequences that control the expression of genes, influencing when, where, and how much gene product is made.
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