Doxylamine Succinate

Below we have described about the uses of Doxylamine Succinate as a sedating antihistamine in allergy relief, cold symptoms, and sleep aid treatment.

Structure of Doxylamine Succinate

  • It is a first-generation antihistamine with a tricyclic structure.
  • It is paired with succinic acid to form a salt, improving solubility.
  • Chemical Formula: C₁₉H₂₉NO₃·C₄H₆O₄

Structure of Doxylamine Succinate

Mode of Action

  • Functions as an H₁-receptor antagonist with anticholinergic and sedative properties.
  • It inhibits the action of histamine at peripheral and central H₁ receptors.
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Uses

  • Insomnia: Used as a short-term treatment for sleep disturbances.
  • Allergic Reactions: Relieves symptoms of allergic rhinitis and urticaria.
  • Cold Symptoms: Alleviates runny nose and sneezing.

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