Ethotoin

  • Ethotoin is prescribed for the management of generalized tonic-clonic and partial seizures.
  •  It stabilizes neuronal membranes by reducing repetitive firing, controlling epileptic activity.

Chemical Formula:

  • C₁₁H₁₆N₂O₂

Chemical Structure of Ethotoin

Mechanism:

  • Sodium channel blocker
  • Less potent than phenytoin
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Therapeutic Uses of Ethotoin:

  • Tonic-clonic seizures
  • Partial seizures

Side Effects of Ethotoin:

  • Sedation
  • GI upset
  • Ataxia
  • Less severe toxicity vs. phenytoin

Notes:

Rarely used today

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