Introduction to Eye Lotions:
- Eye lotions are sterile aqueous solutions used to wash or irrigate the eyes.
- They help remove debris, chemicals, or other foreign materials.
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Components:
- Active Ingredient: Similar to ointments, can include both hydrophilic and lipophilic drugs.
- Emollients and Lubricants: To provide moisturizing effects.
- Thickeners: To achieve desired viscosity without being too thick.
- Preservatives: If intended for multi-dose use.
Formulation Considerations:
- Consistency: Must be smooth and spreadable without being too thick.
- Retention and Comfort: Longer contact time than drops but less greasy than ointments.
- Compatibility: Ensuring that the formulation does not interfere with vision or cause irritation.
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Advantages of Eye Lotions:
- Enhanced Comfort: Less greasy than ointments, leading to better patient compliance.
- Moderate Retention Time: Offers a balance between prolonged contact and ease of use.
Examples:
- Antiallergic Lotions: Combines antihistamines with lubricants.
- Moisturizing Lotion: For dry eye treatment.
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Method of Preparation:
- Solution Preparation: Dissolve ingredients in sterile water.
- Filtration: Filter through a sterilizing filter (0.22 µm).
- Packaging: Filled into single-use or multi-dose containers under aseptic conditions.
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