Felodipine is a calcium channel blocker that treats high blood pressure and angina by relaxing blood vessels and lowering heart workload.
Structure of Felodipine
- Felodipine is a dihydropyridine calcium channel blocker with a substituted phenyl ring and a methoxyethyl side chain attached to the dihydropyridine core.
- Chemical Formula: C₂₂H₂₄N₂O₅
Mode of Action
- Calcium Channel Blocking: Selectively inhibits L-type calcium channels in vascular smooth muscle.
- Vasodilation: Promotes peripheral arterial relaxation, lowering blood pressure.
- Reduced Cardiac Effects: Minimal impact on heart rate and contractility.
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Uses
- Hypertension: Lowers blood pressure by causing vasodilation.
- Angina Pectoris: Relieves chest pain by reducing myocardial oxygen demand.
- Peripheral Arterial Disease: Improves blood flow to peripheral tissues.
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