- Flow Properties Of Powders describe how particles move, pack, and discharge in pharmaceutical processing.
- Flow Properties Of Powders affect mixing, granulation, tableting, and overall product quality.
- Powder flow is critical for operations like tablet compression, capsule filling, and granulation.
Methods to Evaluate Flow:
1 Angle of Repose
- Angle formed when a powder is allowed to fall freely and form a heap.
$\tan \theta = \tfrac{h}{r}$
- Where:
- θ = angle of repose
- h = height of cone
- r = radius of base
Interpretation:
Angle (°) | Flow Characteristics |
<25 | Excellent |
25–30 | Good |
30–40 | Passable |
>40 | Poor |
2. Compressibility Index (Carr’s Index)
$\text{Carr’s Index} = \left( \tfrac{\rho_{\text{tap}} – \rho_{b}}{\rho_{\text{tap}}} \right) \times 100$
Interpretation:
Index (
Flow Properties |
|
5–15 | Excellent |
16–20 | Good |
21–25 | Fair |
>25 | Poor |
3. Hausner Ratio
$\text{Hausner Ratio} = \tfrac{\rho_{\text{tap}}}{\rho_{b}}$
Interpretation:
Ratio | Flow Properties |
1.00–1.11 | Excellent |
1.12–1.18 | Good |
1.19–1.25 | Fair |
>1.25 | Poor |