Gelatin

  • Gelatin is a protein from collagen, widely used in pharmaceuticals, food, and cosmetics for its gelling properties.
  • Gelatin is used in capsules, tablets, emulsions, and as a stabilizer, providing strength, clarity, and easy digestibility.

General Information

  • Synonyms: Animal Glue, Collagen Hydrolysate
  • Biological Source:
    • Derived from collagen found in the skin, bones, and connective tissues of cattle and pigs.
  • Family: Not applicable (Derived from animals).
  • Geographical Source:
    • Produced in India, USA, Brazil, China, Germany.
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Macroscopical Characters of Gelatin

  • Color: Light yellow to brown.
  • Texture: Brittle when dry, gel-like when hydrated.
  • Taste: Tasteless.
  • Odor: Odorless.

Chemical Constituents of Gelatin

  • Proteins: Hydrolyzed collagen composed of glycine, proline, hydroxyproline.
  • Moisture: < 15
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Preparation of Gelatin

  1. Extraction: Collagen is extracted from bones/skin by boiling.
  2. Purification: Acid or alkaline treatment to break down collagen.
  3. Drying & Grinding: Filtered, concentrated, dried into sheets or powder.

Evaluation

  • Solubility: Soluble in hot water, forms a gel on cooling.
  • Purity Tests:
    • Biuret Test → Violet color indicates proteins.
    • Foaming Test → Gelatin forms foam in aqueous solution.
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Preservation & Storage

  • Stored in airtight containers to prevent moisture absorption and microbial contamination.

Therapeutic Uses

  • Used in capsule manufacturing (soft and hard gelatins capsules).
  • Wound healing (collagen source in skin treatments).
  • Nutritional supplement for joint and bone health.
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Commercial Utility

  • Used in food industry (gelling agent in jellies, marshmallows).
  • Used in cosmetics (face masks, shampoos).
  • Used in pharmaceuticals (coating agent in tablets).

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