- Importance of Base Adsorption and Minim/Gram Factors lies in selecting suitable suppository bases that can absorb the drug without altering its efficacy, ensuring uniformity and stability.
- Importance of Base Adsorption and Minim/Gram Factors is crucial for calculating the correct base quantity needed per dose, helping maintain accurate drug delivery and therapeutic effect
Base Adsorption:
- Base adsorption is the weight of the solid drug or excipients adsorbed per gram of liquid carrier (base).
- This concept is crucial when suspending drugs in the liquid or semi-solid fill.
Advertisements
Significance:
- Prevents sedimentation of the drug within the capsule.
- Improves uniformity and ensures consistent drug delivery.
- Helps in calculating the fill weight for accurate dosing.
Minim/Gram Factor:
- Minim/gram factor is a measure of the weight of the fill material (in grams) that corresponds to one minim of the formulation.
Advertisements
Importances:
- Ensures proper compatibility of the liquid fill material with the shell.
- Determines the amount of liquid fill that can be encapsulated within a specific capsule size.
Thank you for reading from Firsthope's notes, don't forget to check YouTube videos!
Advertisements
