Indole is a bicyclic heterocyclic compound found in tryptophan, alkaloids, and widely used in pharmaceuticals and organic synthesis.
Chemical Formula of Indole:
- C₈H₇N
Physical Properties of Indole:
| Property | Value |
| Appearance | White to pale yellow crystals |
| Melting Point | ~52 °C |
| Boiling Point | ~254 °C |
| Solubility | Soluble in ethanol, ether, slightly in water |
| Basicity | Very weak (non-basic) |
Medicinal Uses:
- Found in tryptophan (amino acid), serotonin, melatonin.
- Scaffold in anti-inflammatory, antiviral, anticancer, and antidepressant drugs.
- Drug examples:
- Indomethacin (NSAID)
- Sumatriptan (migraine drug)
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