Introduction to Biopharmaceutics explores drug absorption, distribution, metabolism, and excretion with focus on therapeutic effectiveness.
Introduction to Biopharmaceutics
Definition and Scope
- Biopharmaceutics studies the interrelationship between a drug’s physical, chemical, and biological properties and its absorption, distribution, metabolism, and excretion.
- It connects drug formulation with its therapeutic effects.
Importance in Drug Development and Therapy
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Formulation Design:
- Helps in developing dosage forms (e.g., tablets, capsules, injections) that enhance drug availability.
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Therapeutic Efficacy:
- Ensures optimal absorption for effective treatment.
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Safety and Toxicity:
- Prevents treatment failure due to low absorption and toxicity due to excessive absorption.
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Personalized Medicine:
- Aids in dose adjustments based on factors like gastric pH, organ function, and genetic variations.