Ketorolac

• Ketorolac blocks COX enzymes, reducing prostaglandins to provide strong analgesic and anti-inflammatory effects.
• It is a potent NSAID for short-term management of moderate to severe pain.

Chemical Formula:

• C₁₅H₁₃NO₃

Mechanism of Action:

• Potent non-selective COX inhibitor
• Primarily analgesic, weak anti-inflammatory

Uses of Ketorolac:

• Moderate to severe acute pain (short-term, post-op)
• Alternative to opioids

Side Effects of Ketorolac:

• GI bleeding (BBW: max 5 days use)
• Nephrotoxicity
• Platelet inhibition

Notes:

• Available in oral, IM, IV, ophthalmic forms
• Used cautiously in renal impairment

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