Levocetirizine is the active enantiomer of cetirizine, offering enhanced potency and reduced side effects in the treatment of allergic conditions. Structurally, it retains the piperazine ring seen in cetirizine but provides greater selectivity for peripheral H₁ receptors.
Structure of Levocetirizine
- It is the active enantiomer of Cetirizine, featuring a similar piperazine structure with enhanced selectivity.
- Chemical Formula: C₂₂H₂₁ClN₂O₃
Mode of Action
- Selective peripheral H₁-receptor antagonist with higher potency and reduced side effects compared to its racemic mixture.
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Uses
- Allergic Rhinitis: Treats symptoms such as sneezing, itching, and runny nose.
- Chronic Urticaria: Alleviates hives and skin itching.
- Seasonal Allergies: Provides relief from pollen-induced allergic symptoms.
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