Levorphanol Tartrate

• Levorphanol Tartrate is a potent opioid for severe pain and neuropathic conditions.
• It acts on μ, κ, δ opioid receptors with long duration analgesic effects.

Chemical Formula:

• C₁₇H₂₃NO·C₄H₆O₆

Mechanism of Action:

• Full μ-opioid agonist
• Also inhibits NMDA receptors and serotonin/norepinephrine reuptake

Uses of Levorphanol Tartrate:

• Chronic severe pain
• Effective in neuropathic pain

Side Effects of Levorphanol Tartrate:

• Sedation
• Respiratory depression
• Constipation

Notes:

• Long-acting (T½ ~12–16 hours)
• High oral bioavailability

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