- Levorphanol Tartrate is a potent opioid for severe pain and neuropathic conditions.
- It acts on μ, κ, δ opioid receptors with long duration analgesic effects.
Chemical Formula:
- C₁₇H₂₃NO·C₄H₆O₆
Mechanism of Action:
- Full μ-opioid agonist
- Also inhibits NMDA receptors and serotonin/norepinephrine reuptake
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Uses of Levorphanol Tartrate:
- Chronic severe pain
- Effective in neuropathic pain
Side Effects of Levorphanol Tartrate:
- Sedation
- Respiratory depression
- Constipation
Notes:
- Long-acting (T½ ~12–16 hours)
- High oral bioavailability
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