Liquid Interface

Definition of Liquid Interface

  • A liquid interfaces is the boundary between two immiscible liquid phases or between a liquid and another phase (solid or gas).
  • At this boundary, the physical and chemical properties differ from those in the bulk phases due to molecular interactions unique to the interface.

Types of Liquid Interface

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  1. Liquid-Gas Interface: Examples include the surface of water exposed to air.
  2. Liquid-Liquid Interfaces: Occurs between two immiscible liquids like oil and water.
  3. Liquid-Solid Interfaces: Exists where a liquid is in contact with a solid surface, such as water on glass.

Importance in Pharmaceuticals

  1. Stability of Dosage Forms: Interfaces play a crucial role in the stability of emulsions and suspensions.
  2. Drug Absorption: The interaction of drug molecules at biological interfaces affects absorption and bioavailability.
  3. Surface Phenomena Control: Understanding liquid interfaces helps in manipulating wetting, spreading, and adhesion properties.
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