- Lorazepam is a drug which treats anxiety, insomnia, and seizures with calming effects.
- Lorazepam, a benzodiazepine, enhances GABA activity for sedation.
Chemical Formula:
- C₁₅H₁₀Cl₂N₂O₂
Mechanism of Lorazepam:
- Enhances GABAergic inhibition
- Intermediate-acting BZD with no active metabolites
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Uses of Lorazepam:
- Status epilepticus (IV)
- Anxiety
- Pre-op sedation
Side Effects:
- CNS depression
- Amnesia
- Less hepatic metabolism → safe in elderly/liver disease
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