Menadione is a synthetic vitamin K used as a coagulant to treat and prevent bleeding caused by vitamin K deficiency.
Structure of Menadione
- Menadione, also known as vitamin K3, is a synthetic compound with a naphthoquinone structure.
- Chemical Formula: C₁₀H₆O₂
Mode of Action
- Provitamin K Activity: Serves as a precursor to active vitamin K forms.
- Coagulation Factor Synthesis: Supports the carboxylation of glutamate residues on clotting factors II, VII, IX, and X.
- Antioxidant Properties: Exhibits free radical scavenging activity.
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Uses
- Vitamin K Deficiency: Treats and prevents bleeding disorders due to inadequate vitamin K.
- Warfarin Reversal: Assists in counteracting warfarin-induced anticoagulation.
- Antioxidant Supplementation: Employed in research settings for its antioxidant effects.
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