- Meperidine Hydrochloride (Pethidine) acts on μ-opioid receptors, producing analgesia and sedation.
- It is an opioid analgesic for moderate to severe pain relief.
Chemical Formula:
- C₁₅H₂₁NO₂·HCl
Mechanism of Action:
- Synthetic μ-opioid agonist
- Also has anticholinergic and local anesthetic properties
Advertisements
Therapeutic Uses of Meperidine Hydrochloride (Pethidine):
- Acute pain
- Obstetric analgesia (short duration)
- Post-anesthesia shivering
Side Effects of Meperidine Hydrochloride (Pethidine):
- CNS effects (dysphoria, tremors, seizures from normeperidine)
- Respiratory depression
- Dry mouth
- Tachycardia (anticholinergic)
Notes:
- Not for chronic use: toxic metabolite (normeperidine) accumulates
- Shorter duration than morphine
Thank you for reading from Firsthope's notes, don't forget to check YouTube videos!
