- Mephenytoin stabilizes neuronal membranes by reducing repetitive firing through sodium channel blockade.
- It is an anticonvulsant used in managing generalized tonic-clonic and partial seizures.
Chemical Formula:
- C₁₂H₁₄N₂O₂
Mechanism of Mephenytoin:
- Sodium channel blocker (like phenytoin)
- Rapid oral absorption
Uses of Mephenytoin:
- Tonic-clonic and partial seizures (historical)
Side Effects:
- Aplastic anemia (rare but serious)
- Drowsiness, ataxia
- No longer preferred
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