Mephenytoin

  • Mephenytoin stabilizes neuronal membranes by reducing repetitive firing through sodium channel blockade.
  • It is an anticonvulsant used in managing generalized tonic-clonic and partial seizures.

Chemical Formula:

  • C₁₂H₁₄N₂O₂

Chemical Structure of Mephenytoin

Mechanism of Mephenytoin:

  • Sodium channel blocker (like phenytoin)
  • Rapid oral absorption

Uses of Mephenytoin:

  • Tonic-clonic and partial seizures (historical)
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Side Effects:

  • Aplastic anemia (rare but serious)
  • Drowsiness, ataxia
  • No longer preferred

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