- Methsuximide is prescribed for controlling absence seizures when other drugs are less effective.
- It reduces abnormal neuronal firing by blocking T-type calcium channels in the CNS.
Chemical Formula:
- C₁₂H₁₅NO₂
Mechanism of Methsuximide :
- T-type Ca²⁺ channel blockade
Therapeutic Uses of Methsuximide:
- Refractory absence seizures
- May be used when ethosuximide fails
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Side Effects:
- CNS effects: dizziness, ataxia
- GI irritation
- Hepatotoxicity
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