Myasthenia Gravis (MG)

Myasthenia Gravis (MG) is an autoimmune disorder causing muscle weakness due to impaired neuromuscular transmission.

  • A chronic autoimmune neuromuscular disorder that causes weakness in the skeletal muscles.

Cause of Myasthenia Gravis (MG):

  • Autoantibodies block or destroy acetylcholine receptors at the neuromuscular junction.

Symptoms of Myasthenia Gravis (MG):

  • Muscle weakness that worsens with activity (fatigue)
  • Drooping eyelids (ptosis)
  • Double vision (diplopia)
  • Difficulty swallowing or speaking
  • Weakness in limbs or respiratory muscles
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Treatment:

  • Acetylcholinesterase inhibitors (e.g., pyridostigmine)
  • Immunosuppressants (e.g., corticosteroids, azathioprine)
  • IVIG or plasmapheresis (especially in crisis)
  • Thymectomy (if thymoma present)

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