- Naproxen blocks COX enzymes, reducing prostaglandins to relieve pain, fever, and swelling.
- It is an NSAID used for arthritis, muscle pain, menstrual cramps, and inflammation.
Chemical Formula:
- C₁₄H₁₄O₃
Mechanism of Naproxen:
- Reversible COX-1/COX-2 inhibitor
Uses of Naproxen:
- Arthritis, ankylosing spondylitis
- Dysmenorrhea
- Fever, inflammation
Side Effects:
- GI discomfort
- Cardiovascular risk (less than some NSAIDs)
- Fluid retention
Notes:
Only S-enantiomer used therapeutically
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