Naproxen

  • Naproxen blocks COX enzymes, reducing prostaglandins to relieve pain, fever, and swelling.
  • It is an NSAID used for arthritis, muscle pain, menstrual cramps, and inflammation.

Chemical Formula:

  • C₁₄H₁₄O₃

 

Chemical Structure of Naproxen

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Mechanism of Naproxen:

  • Reversible COX-1/COX-2 inhibitor

Uses of Naproxen:

  • Arthritis, ankylosing spondylitis
  • Dysmenorrhea
  • Fever, inflammation

Side Effects:

  • GI discomfort
  • Cardiovascular risk (less than some NSAIDs)
  • Fluid retention

Notes:

Only S-enantiomer used therapeutically

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