- Non-Newtonian systems are fluids that do not follow Newton’s law of viscosity.
Unlike Newtonian fluids (such as water or alcohol), their viscosity is not constant and varies depending on factors like shear rate, shear stress, and, in some cases, time. - This makes them essential considerations in the formulation and behavior of various pharmaceutical products.
Common Pharmaceutical Applications
- Non-Newtonian behavior is frequently observed in pharmaceutical dosage forms such as:
-
- Suspensions
- Emulsions
- Creams
- Gels
- Ointments
- Polymer solutions
Key Non-Newtonian Behaviors
- Plastic Flow
- Pseudoplastic Flow (Shear-Thinning)
- Dilatant Flow (Shear-Thickening)
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