Norgestrel is a synthetic progestin used in contraceptives to prevent ovulation and regulate menstrual cycles.
Structure of Norgestrel
- Norgestrel is a synthetic progestogen with a 19-nor steroid structure, lacking the carbon at position 19 of the progesterone backbone.
- Chemical Formula: C₂₀H₂₉NO₂
Mode of Action
- Progestogen Activity: Mimics the effects of natural progesterone, regulating the menstrual cycle and preventing ovulation.
- Endometrial Stabilization: Thins the endometrial lining, making it unsuitable for implantation.
- Cervical Mucus Thickening: Increases viscosity of cervical mucus, impeding sperm penetration.
Advertisements
Uses
- Oral Contraception: Used in combination with estrogens in combined oral contraceptive pills to prevent pregnancy.
- Menstrual Disorders: Manages irregular menstrual cycles and reduces menstrual bleeding.
- Endometriosis: Helps in reducing the growth of endometrial tissue outside the uterus.
Thank you for reading from Firsthope's notes, don't forget to check YouTube videos!
