- Paraldehyde is a central nervous system depressant, promoting sedation and muscle relaxation.
- It treats acute seizures and alcohol withdrawal symptoms.
Chemical Formula:
- C₆H₁₂O₃
Mechanism of Action:
- CNS depressant: exact mechanism unclear.
- Possibly acts on GABA-A receptors and enhances inhibitory tone.
Advertisements
Therapeutic Uses of Paraldehyde:
- Delirium tremens (alcohol withdrawal)
- Status epilepticus (historical use)
- Sedation (limited due to toxicity)
Side Effects of Paraldehyde:
- Strong, unpleasant odor/taste
- Respiratory depression
- Hepatotoxicity
- Local irritation (esp. rectal use)
Notes:
Largely discontinued; historically important.
Thank you for reading from Firsthope's notes, don't forget to check YouTube videos!
