- Parathion is a highly toxic organophosphate pesticide used for pest control in crops.
- Parathion exposure can cause severe poisoning, affecting the nervous system.
Chemical Formula:
- C₁₀H₁₄NO₅PS
Mechanism of Action:
- Irreversible AChE inhibitor after bioactivation to paraoxon
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Uses:
- Agricultural insecticide (not for therapeutic use)
Side Effects (Toxicity):
- SLUDGE syndrome: Salivation, Lacrimation, Urination, Diarrhea, GI upset, Emesis
- Seizures
- Respiratory failure
- Requires antidote (atropine + pralidoxime)
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