Pentobarbital

  • Pentobarbital enhances GABA activity, acting as a short-acting barbiturate sedative-hypnotic.
  • It is used for insomnia, preoperative sedation, and seizure control in emergencies.

Chemical Formula:

  • C₁₁H₁₈N₂O₃

Chemical Structure of Pentobarbital

Mechanism of Pentobarbital:

  • Short-acting GABA-A receptor agonist.
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Therapeutic Uses of Pentobarbital:

  • Sedation
  • Anesthesia induction (older use)
  • Euthanasia in veterinary and medical contexts

Side Effects:

  • Severe respiratory depression
  • High abuse potential
  • Lethal in overdose

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