- Phenacemide is an anticonvulsant used in refractory epilepsy when other treatments fail.
- It stabilizes neuronal activity, reducing abnormal electrical discharges in the brain.
Formula:
- C₉H₁₀N₂O₂
Mechanism of Phenacemide:
- Unclear; likely stabilizes neuronal membranes
- Possibly inhibits Na⁺ channels
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Uses of Phenacemide:
- Refractory epilepsy (no longer used)
Side Effects:
- Severe toxicity:
- Aplastic anemia
- Liver damage
- Psychosis
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