Piroxicam

  • Piroxicam blocks COX enzymes, reducing prostaglandin synthesis to relieve pain and swelling.
  • It is an NSAID for long-term management of arthritis, pain, and inflammation.

Chemical Formula:

  • C₁₅H₁₃N₃O₄S

Chemical Structure of Piroxicam

Mechanism of Piroxicam:

  • Non-selective COX inhibitor
  • Long half-life (~50 hrs)
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Uses of Piroxicam:

  • Chronic inflammatory conditions (OA, RA)
  • Once-daily dosing

Side Effects:

  • GI irritation/ulceration
  • Photosensitivity
  • Headache

Notes:

  • Long-acting alternative to other NSAIDs

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