- Pralidoxime Chloride (2-PAM): Antidote for organophosphate poisoning, reactivates acetylcholinesterase.
- Pralidoxime Chloride (2-PAM): Restores normal neuromuscular function, used in emergency toxicology.
Chemical Formula:
- C₇H₉ClN₂O
Mechanism of Action:
- Reactivates phosphorylated AChE by removing the phosphate group (only effective before “aging” of the bond).
- Must be given early in organophosphate poisoning.
Uses of Pralidoxime Chloride (2-PAM):
- Antidote for organophosphate poisoning (used with atropine)
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Side Effects of Pralidoxime Chloride (2-PAM):
- Hypertension
- Dizziness
- Muscle rigidity
- Blurred vision
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