Prochlorperazine Maleate

  • Prochlorperazine Maleate is a dopamine antagonist, blocking D2 receptors in the brain to control symptoms.
  • Prochlorperazine Maleate treats nausea, vomiting, and psychotic disorders like schizophrenia.

Chemical Formula:

  • C₂₀H₂₄ClN₃S·C₄H₄O₄

Chemical Structure of Prochlorperazine Maleate

Mechanism of Action:

  • Strong D2 receptor blockade
  • Acts on chemoreceptor trigger
  • (CTZ)
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Therapeutic Uses of Prochlorperazine Maleate:

  • Nausea and vomiting
  • Vertigo
  • Schizophrenia
  • Migraine-associated nausea

Side Effects of Prochlorperazine Maleate:

  • High EPS risk
  • Dystonia
  • Sedation
  • Dry mouth
  • Tardive dyskinesia (long-term use)

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