- Propoxyphene Hydrochloride acts as a weak opioid agonist, binding to CNS receptors to reduce pain.
- It is used for mild to moderate pain relief with limited efficacy.
Chemical Formula:
- C₂₂H₂₉NO₂·HCl
Mechanism of Action:
- Weak μ-opioid receptor agonist
- Structurally related to methadone, but much lower potency
Uses of Propoxyphene Hydrochloride:
- Mild to moderate pain
- Formerly combined with acetaminophen (Darvocet)
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Side Effects of Propoxyphene Hydrochloride:
- Constipation, dizziness
- Cardiotoxicity at high doses
- Abuse risk
Notes:
- Withdrawn from U.S. market due to fatal arrhythmias
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