Protective Action of Colloids

• Protective Action of Colloids prevents coagulation by stabilizing dispersed particles.
• Protective Action of Colloids is vital in pharmaceuticals, food, and industrial formulations.

Definition:

• The ability of lyophilic colloids to protect lyophobic colloids from coagulation by electrolytes.

Mechanism:

• Lyophilic colloids form a protective layer around lyophobic particles, preventing them from aggregating.

Protective Colloid:

• A lyophilic colloid (such as gelatin or starch) forms a protective layer around lyophobic particles, preventing them from aggregating.

Gold Number (measure of protective ability):

• Defined as the minimum amount of protective colloid (mg) required to prevent coagulation of 10 mL of gold sol by 1 mL of 10
• Lower gold number = better protective action.

Applications:

• Stabilization of colloidal drug products.

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