Pyrazole is a five-membered aromatic heterocyclic compound with two adjacent nitrogen atoms, used in medicines and agrochemicals.
Chemical Formula of Pyrazole:
- C₃H₄N₂
Physical Properties:
| Property | Value |
| Appearance | White crystalline solid |
| Melting Point | ~66 °C |
| Boiling Point | ~186 °C |
| Solubility | Soluble in water, alcohol, ether |
| Basicity | Weakly basic |
Medicinal Uses:
- Found in analgesic, anti-inflammatory, antipyretic, and antidepressant drugs.
- Examples:
- Phenylbutazone: Anti-inflammatory
- Celecoxib: COX-2 inhibitor (pyrazole ring)
- Sildenafil (Viagra): Pyrazole moiety contributes to activity
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