Reaction Kinetics and Its Relevance to Drug Stability

  • Reaction kinetics sand Its Relevance to Drug Stability is the study of rates at which chemical reactions occur. In pharmaceuticals, it helps:
  • Predict how long a drug remains stable
  • Design appropriate storage conditions
  • Optimize formulations
  • Set expiration dates
  • A general rate law expresses how the rate of reaction depends on the concentration of reactants.

General Rate Law:

$\text{Rate} = -\frac{d[A]}{dt} = k[A]^n$

  • Where:
    • [A] = concentration of drug
    • k = rate constant
    • n = order of reaction (can be 0, 1, 2…)
    • $\frac{d[A]}{dt}$ = rate of disappearance of An over time

 

Advertisements

Click Here to Watch the Best Pharma Videos!

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.