- Risperidone blocks dopamine D2 and serotonin 5-HT2 receptors, stabilizing mood and behavior.
- It treats schizophrenia, bipolar disorder, and irritability in autism spectrum disorder.
Chemical Formula:
- C₂₃H₂₇FN₄O₂
Mechanism of Risperidone:
- Antagonist at D2 and 5-HT2A
- Also affects α1, H1 receptors
Uses of Risperidone:
- Schizophrenia
- Bipolar disorder
- Irritability in autism
Side Effects:
- Moderate EPS (esp. at high doses)
- Weight gain
- Hyperprolactinemia
- Orthostatic hypotension
Notes:
- First-line atypical antipsychotic
- Available in long-acting injectable (Risperdal Consta)
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