Ruta (Flavonoids)

Introduction to Ruta (Flavonoids):

• Ruta, primarily Ruta graveolens (Rue), is rich in flavonoid and exhibits anti-inflammatory, antispasmodic, and antimicrobial properties.

Synonyms of Ruta (Flavonoids):

• Common name: Rue
• Scientific name: Ruta graveolens
• Other names: Herb-of-grace, Common rue

Biological Source:

• Derived from the aerial parts (leaves and stems) of Ruta graveolens.

Family:

• Rutaceae

Composition:

• Major flavonoids:
  • Rutin (quercetin glycoside)
  • Quercetin
  • Hesperidin
  • Apigenin

Chemistry:

• Class: Flavonoids (flavonols and flavones).
• Structure:
  • Rutin: Glycoside of quercetin with sugar moieties.
  • Quercetin: A polyhydroxy flavonoid with antioxidant activity.
• Solubility: Water-soluble due to glycosidic linkages.

Therapeutic Uses:

• Antioxidant: Rutin and quercetin combat oxidative stress.
• Capillary Strengthening: Rutin enhances capillary resistance, aiding conditions like varicose veins and hemorrhoids.
• Anti-inflammatory: Rutin and hesperidin inhibit inflammatory pathways.
• Antispasmodic: Relaxes smooth muscles, alleviating gastrointestinal and uterine spasms.
• Antimicrobial: Effective against various bacteria and fungi.

Commercial Applications of Ruta (Flavonoids):

• Rutin supplements: For vascular health (varicose veins, hemorrhoids).
• Herbal teas/tinctures: Used for antispasmodic and sedative effects.
• Cosmetics: Rutin and quercetin in anti-aging and skin-lightening products.

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