- Secobarbital is a barbiturate used for short-term insomnia treatment and preoperative sedation.
- It depresses CNS activity by enhancing GABA action, producing sedative and hypnotic effects.
Chemical Formula:
- C₁₂H₁₈N₂O₃
Mechanism of Secobarbital:
- Short-acting barbiturate; increases GABA-mediated chloride influx.
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Therapeutic Uses of Secobarbital:
- Hypnotic
- Preoperative sedation
- Rarely used today due to dependence risk
Side Effects:
- High abuse potential
- Tolerance
- Withdrawal symptoms
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