- Sevoflurane acts on CNS by enhancing GABA activity, providing smooth onset and quick recovery.
- It is an inhalation anesthetic used for rapid induction and maintenance of general anesthesia.
Chemical Formula:
- C₄H₃F₇O
Mechanism of Sevoflurane:
- Potentiates GABA-A and glycine receptors
- Fast onset due to low blood/gas solubility
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Uses of Sevoflurane:
- Induction in children (non-pungent)
- Maintenance
Side Effects:
- Nephrotoxicity (via Compound A in closed circuits)
- Hypotension
- Rare emergence delirium
Notes:
- Sweet-smelling, non-irritating
- Most popular inhalation induction agent
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