Thiamylal Sodium

  • Thiamylal Sodium enhances GABA action in the CNS, producing rapid sedative and hypnotic effects.
  • It is a barbiturate used for induction of anesthesia and short surgical procedures.

Chemical Formula:

  • C₁₁H₁₇N₂NaO₂S

Chemical Structure of Thiamylal Sodium

Mechanism of Thiamylal Sodium:

  • Potentiates GABA-A receptor
  • Highly lipophilic → rapid onset of CNS depression
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Uses of Thiamylal Sodium:

  • Anesthesia induction
  • Brief surgical anesthesia

Side Effects:

  • Respiratory depression
  • Hypotension
  • Reflex tachycardia
  • Laryngospasm (esp. in children)

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