- Thiopental Sodium is a barbiturate that enhances GABA action, causing rapid CNS depression.
- It is used for induction of anesthesia and short-term surgical procedures.
Chemical Formula:
- C₁₁H₁₇N₂NaO₂S
Mechanism of Action:
- Enhances GABA-A receptor function
- Depresses reticular activating system
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Uses of Thiopental Sodium:
- Induction of anesthesia
- Control of seizures
- Medically induced coma (neuroprotection)
Side Effects of Thiopental Sodium:
- Apnea
- Hypotension
- Hangover effect (due to slow redistribution)
- Arterial necrosis if extravasated
