Thiopental Sodium

• Thiopental Sodium is a barbiturate that enhances GABA action, causing rapid CNS depression.
• It is used for induction of anesthesia and short-term surgical procedures.

Chemical Formula:

• C₁₁H₁₇N₂NaO₂S

Mechanism of Action:

• Enhances GABA-A receptor function
• Depresses reticular activating system

Uses of Thiopental Sodium:

• Induction of anesthesia
• Control of seizures
• Medically induced coma (neuroprotection)

Side Effects of Thiopental Sodium:

• Apnea
• Hypotension
• Hangover effect (due to slow redistribution)
• Arterial necrosis if extravasated

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