Thioridazine Hydrochloride

  • Thioridazine Hydrochloride is a typical antipsychotic, blocking dopamine receptors to reduce psychotic activity in the brain.
  • It treats schizophrenia and psychotic disorders by managing symptoms like agitation and hallucinations.

Chemical Formula:

  • C₂₁H₂₇ClN₂S₂·HCl

Mechanism of Action:

  • D2 receptor antagonist
  • Also blocks muscarinic, alpha, and H1 receptors

Uses of Thioridazine Hydrochloride:

  • Schizophrenia (especially in treatment-resistant or sensitive patients)
  • Mild psychosis
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Side Effects of Thioridazine Hydrochloride:

  • Low EPS risk
  • High anticholinergic effects
  • QT prolongation, retinal pigmentation (dose-related)
  • Sedation, hypotension

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