Thyroid Cancer

Thyroid Cancer Introduction

  • Thyroid cancer arises from the cells of the thyroid gland.
  • It is generally highly treatable and often curable, especially when detected early.

Types of Thyroid Cancer

  1. Papillary:

    • The most common and least aggressive type.
  2. Follicular:

    • Includes Hurtled cell carcinoma; tends to spread to distant organs.
  3. Medullary:

    • Arises from C cells that produce calcitonin; may be part of genetic syndromes.
  4. Anaplastic:

    • Rare and highly aggressive.
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Causes

  1. Genetic Mutations: Can lead to uncontrolled cell growth.
  2. Radiation Exposure: Increased risk, particularly from childhood radiation exposure.
  3. Family History: Genetic predisposition in some types of cancer.

Symptoms

  • A lump or swelling in the neck.
  • Hoarseness or voice changes.
  • Difficulty swallowing or breathing.
  • Persistent cough not related to a cold.
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Diagnosis

  1. Ultrasound: To visualize thyroid nodules and lymph nodes.
  2. Fine-Needle Aspiration (FNA) Biopsy: To examine cells for cancer.
  3. Blood Tests: To measure levels of thyroid hormones and calcitonin.
  4. Radioactive Iodine Scan: To assess thyroid function and detect metastasis.
  5. Genetic Testing: For hereditary forms of thyroid cancer.

Treatment

  1. Surgery: Primary treatment, often involving thyroidectomy (removal of part or all of the thyroid gland).
  2. Radioactive Iodine Therapy: To destroy remaining thyroid tissue and treat metastasis.
  3. Thyroid Hormone Therapy: To replace hormones and suppress TSH (thyroid-stimulating hormone) to prevent cancer recurrence.
  4. External Radiation Therapy: For advanced or inoperable cancer.
  5. Chemotherapy: Used in some cases of anaplastic this cancer.
  6. Targeted Therapy: For advanced cancer not responding to other treatments.
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