Trifluoperazine Hydrochloride

• Trifluoperazine Hydrochloride is a typical antipsychotic, reducing psychotic symptoms through dopamine antagonism.
• It treats schizophrenia, anxiety, and severe nausea by blocking dopamine receptors.

Chemical Formula:

• C₂₁H₂₄F₃N₃S·HCl

Mechanism of Action:

• Potent D2 antagonist, especially in mesolimbic tract
• Minimal effect on muscarinic/H1 receptors

Therapeutic Uses of Trifluoperazine Hydrochloride:

• Schizophrenia
• Acute anxiety (short-term use)

Side Effects of Trifluoperazine Hydrochloride:

• Very high EPS risk
• Low sedation
• Less anticholinergic activity

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