Trimeprazine Tartrate is a first-generation H₁-antihistamine effective in treating allergic reactions, urticaria, and cold-related symptoms. Structurally, it is a dibenzocycloheptene derivative featuring a piperazine ring substituted with methyl groups. The tartrate salt enhances its solubility.
Structure of Trimeprazine Tartrate
- Trimeprazine is a dibenzocycloheptene derivative with a piperazine ring substituted with methyl groups.
- It forms a salt with tartaric acid to improve solubility.
- Chemical Formula: C₂₂H₂₄N₂·C₄H₆O₆
Mode of Action
- Acts as an H₁-receptor antagonist with anticholinergic and sedative effects.
- It blocks histamine-mediated allergic responses.
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Uses
- Allergic Reactions: Treats symptoms such as sneezing, itching, and runny nose.
- Urticaria: Alleviates hives and skin itching.
- Cold Symptoms: Helps reduce nasal congestion and other related discomforts.
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