Triphelenamine Hydrochloride is a first-generation antihistamine known for its effectiveness in treating allergic conditions such as rhinitis, urticaria, and cold symptoms.
Structure of Triphelenamine Hydrochloride
- Triphelenamine features a tricyclic structure with three benzene rings fused together, connected to an ethylamine side chain.
- The hydrochloride salt enhances solubility.
- Chemical Formula: C₁₄H₁₈N·HCl
Mode of Action
- Blocks peripheral and central H₁ receptors, providing antihistaminic and sedative effects.
- It also exhibits anticholinergic properties.
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Uses
- Allergic Rhinitis: Manages symptoms like sneezing and itching.
- Urticaria: Provides relief from hives and skin itching.
- Cold Symptoms: Helps reduce nasal discharge and congestion.
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