Voglibose is an alpha-glucosidase inhibitor antidiabetic drug that helps control post-meal blood sugar by delaying carbohydrate absorption.
Structure of Voglibose
- It is an iminosugar derivative with a cyclitol backbone, structurally modified to enhance specificity for intestinal alpha-glucosidases.
- Chemical Formula: C₁₂H₂₀N₂O₈
Mode of Action
- Alpha-Glucosidase Inhibition: Specifically inhibits intestinal enzymes, delaying carbohydrate digestion.
- Postprandial Glycemic Control: Prevents rapid spikes in blood glucose after meals.
Uses
- Type 2 Diabetes Mellitus: Effective in managing postprandial hyperglycemia.
- Combination Therapy: Often combined with other antidiabetic agents for comprehensive glycemic management.
Side Effects of Voglibose
- Gastrointestinal Issues: Bloating, diarrhea, and flatulence due to fermentation of undigested carbohydrates.
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