Voglibose

Voglibose is an alpha-glucosidase inhibitor antidiabetic drug that helps control post-meal blood sugar by delaying carbohydrate absorption.

Structure of Voglibose

  • It is an iminosugar derivative with a cyclitol backbone, structurally modified to enhance specificity for intestinal alpha-glucosidases.
  • Chemical Formula: C₁₂H₂₀N₂O₈

Structure of Voglibose

Mode of Action

  • Alpha-Glucosidase Inhibition: Specifically inhibits intestinal enzymes, delaying carbohydrate digestion.
  • Postprandial Glycemic Control: Prevents rapid spikes in blood glucose after meals.
Advertisements

Uses

  • Type 2 Diabetes Mellitus: Effective in managing postprandial hyperglycemia.
  • Combination Therapy: Often combined with other antidiabetic agents for comprehensive glycemic management.

Side Effects of Voglibose

  • Gastrointestinal Issues: Bloating, diarrhea, and flatulence due to fermentation of undigested carbohydrates.

Thank you for reading from Firsthope's notes, don't forget to check YouTube videos!

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.